View abstract. Kocharian, A., Shabanian, R., Rafiei-Khorgami, M., Kiani, A., and Heidari-Bateni, G. Coenzyme Q10 improves diastolic function in children with idiopathic dilated cardiomyopathy. Belaia, O. L., Kalmykova, V. I., Ivanova, L. A., and Kochergina, L. G. [Experience in coenzyme Q10 application in complex therapy of coronary heart disease with dyslipidemia]. Some research shows that taking coenzyme Q10 might help reduce some, Tissue damage caused when there is limited blood flow and then blood flow is restored (, Migraine. Mol Aspects Med 1997;18 Suppl:S307-9. J Neurol Sci 1998;156:41-6. Pandolfo, M. Introduction. One large research study shows that taking coenzyme Q10 in large doses (2.4 grams daily) for up to 5 years does not stop Huntington disease symptoms from getting worse. People get 7080% of their vitamin D from exposure to sunlight. Mol Aspects Med 1997;18 Suppl:S213-9. Digiesi V, Cantini F, Bisi G, and et al. Int.J Sport Nutr Exerc.Metab 2009;19(3):243-258. 2001;49(5):590-596. View abstract. List of Orphan Designations and Approvals. View abstract. 2011;11(4):623-625. 2012;259(2):284-291. Biofactors 2008;32(1-4):231-235. Adv.Exp.Med.Biol. Mol.Aspects Med 1994;15 Suppl:s97-s102. Scaglione F, Lundstrom B, Barbieri B, and et al. 2nd ed. The Huntington Study Group. But other research shows that taking a form of coenzyme Q10 called ubiquinol doesn't prevent death. Ozaki, A., Muromachi, A., Sumi, M., Sakai, Y., Morishita, K., and Okamoto, T. Emulsification of coenzyme Q10 using gum arabic increases bioavailability in rats and human and improves food-processing suitability. Tran MT, Mitchell TM, Kennedy DT, Giles JT. View abstract. Increased mitochondrial oxidative damage in patients with sporadic amyotrophic lateral sclerosis. Cyrus-Hajmassy, M. [Bilateral visual deterioration in excessive tobacco and alcohol consumption]. Coenzyme Q10 is a vitamin-like substance found throughout the body, but especially in the heart, liver, kidney, and pancreas. Neuropsychobiology 1997;36:73-82. . 1994;107(1):242-247. View abstract. Kamikawa T, Kobayashi A, Yamashita T, et al. Weakened and enlarged heart (dilated cardiomyopathy). No effect of antioxidant supplementation in triathletes on maximal oxygen uptake, 31P-NMRS detected muscle energy metabolism and muscle fatigue. Altern Ther Health Med. View abstract. Murata, T., Ohtsuka, C., and Terayama, Y. Donovan, L. E. and Severin, N. E. Maternally inherited diabetes and deafness in a North American kindred: tips for making the diagnosis and review of unique management issues. Shinyaku to Rinsho 1970;29:1541-1546. Eur Rev Med Pharmacol Sci 2022;26(13):4698-4704. Coenzyme Q10 supplementation during pregnancy reduces the risk of pre-eclampsia. Hamilton, S. J., Chew, G. T., and Watts, G. F. Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. View abstract. Rusciani, L., Proietti, I., Paradisi, A., Rusciani, A., Guerriero, G., Mammone, A., De Gaetano, A., and Lippa, S. Recombinant interferon alpha-2b and coenzyme Q10 as a postsurgical adjuvant therapy for melanoma: a 3-year trial with recombinant interferon-alpha and 5-year follow-up. View abstract. Sinatra, S. T. Refractory congestive heart failure successfully managed with high dose coenzyme Q10 administration. Derosa G, D'Angelo A, Maffioli P. Coenzyme q10 liquid supplementation in dyslipidemic subjects with statin-related clinical symptoms: a double-blind, randomized, placebo-controlled study. Eriksson JG, Forsen TJ, Mortensen SA, Rohde M. The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus. Rev.Neurol. View abstract. Judy WV, Folkers K, and Hall JH. South Med J 2001;94:1112-7. Ann Thorac Surg 1996;61:829-33. 2009;15(11):R1-R8. Clinical response of myelodysplastic syndromes patients to treatment with coenzyme Q10. 2014;5(3-4):187-97. View abstract. 2019 Oct 21;13:3647-3655. Brain 2011;134(Pt 9):2677-2686. Early research suggests that taking an altered form of coenzyme Q10 called ubiquinol improves dry mouth. View abstract. Islam, J., Uretsky, B. F., and Sierpina, V. S. Heart failure improvement with CoQ10, Hawthorn, and magnesium in a patient scheduled for cardiac resynchronization-defibrillator therapy: a case study. However, there is some early evidence that taking coenzyme Q10 by mouth might be helpful. Kaikkonen, J., Kosonen, L., Nyyssonen, K., Porkkala-Sarataho, E., Salonen, R., Korpela, H., and Salonen, J. T. Effect of combined coenzyme Q10 and d-alpha-tocopheryl acetate supplementation on exercise-induced lipid peroxidation and muscular damage: a placebo-controlled double-blind study in marathon runners. Arch.Anim Nutr. Coenzyme Q10 does not improve simvastatin tolerability in dyslipidemic patients with prior statin-induced myalgia. Weber, C., Sejersgard, Jakobsen T., Mortensen, S. A., Paulsen, G., and Holmer, G. Antioxidative effect of dietary coenzyme Q10 in human blood plasma. View abstract. Early research shows that taking coenzyme Q10 improves symptoms of depression in people over 55 years of age with bipolar disorder. View abstract. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. J Bone Joint Surg Br 1988;70:663-4. Biochem Biophys Res Commun 1995;212:172-7. Esteves, A. R., Arduino, D. M., Swerdlow, R. H., Oliveira, C. R., and Cardoso, S. M. Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids. 2012;40(4):88-95. Pediatr Diabetes 2008;9(6):540-545. View abstract. View abstract. View abstract. 2012;69(8):978-83. Biofactors 2005;25(1-4):235-240. Singh, R. B., Niaz, M. A., Kumar, A., Sindberg, C. D., Moesgaard, S., and Littarru, G. P. Effect on absorption and oxidative stress of different oral Coenzyme Q10 dosages and intake strategy in healthy men. Hearing loss. View abstract. When you first open the package, the flavor jumps right out and smacks you in the face, and it made me think "mmmmm". Low coenzyme Q10 levels seem to be linked with an increased risk of skin cancer. Lodi, R., Hart, P. E., Rajagopalan, B., Taylor, D. J., Crilley, J. G., Bradley, J. L., Blamire, A. M., Manners, D., Styles, P., Schapira, A. H., and Cooper, J. M. Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia. Moradi M, Haghighatdoost F, Feizi A, Larijani B, Azadbakht L. Effect of coenzyme Q10 supplementation on diabetes biomarkers: a systematic review and meta-analysis of randomized controlled clinical trials. View abstract. Alehagen U, Johansson P, Bjornstedt M, et al. Eur J Ophthalmol. Balercia, G., Buldreghini, E., Vignini, A., Tiano, L., Paggi, F., Amoroso, S., Ricciardo-Lamonica, G., Boscaro, M., Lenzi, A., and Littarru, G. Coenzyme Q10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial. Gynecol Endocrinol 2022;38(1):45-9. Lee, B. J., Huang, Y. C., Chen, S. J., and Lin, P. T. Effects of coenzyme Q10 supplementation on inflammatory markers (high-sensitivity C-reactive protein, interleukin-6, and homocysteine) in patients with coronary artery disease. Pharmacol Res. Neurology 2007;68:20-8. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent Migraine. But results from larger studies are inconsistent. 1993;71(8 Suppl):S162-S166. Protective action of L-carnitine and coenzyme Q10 against hepatic triglyceride infiltration induced by hyperbaric oxygen and ethanol. Alzheimer disease. Witte, K. K., Nikitin, N. P., Parker, A. C., von Haehling, S., Volk, H. D., Anker, S. D., Clark, A. L., and Cleland, J. G. The effect of micronutrient supplementation on quality-of-life and left ventricular function in elderly patients with chronic heart failure. 1993;71(8 Suppl):S155-S161. 2006;35(2):158-161. View abstract. 5-24-2001;140(10):307-310. Diaz-Castro J, Mira-Rufino PJ, Moreno-Fernandez J, et al. Mech Ageing Dev 2004;125:41-6. Lockwood K, Moesgaard S, Folkers K. Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10. Farsi F, Heshmati J, Keshtkar A, et al. Cancer. View abstract. Kuklinski, B., Weissenbacher, E., and Fahnrich, A. Coenzyme Q10 and antioxidants in acute myocardial infarction. 2011;34(4):211-217. Research on coenzyme Q10 in clinical medicine and in immunomodulation. 2008;5(4):558-568. Some early research shows that taking coenzyme Q10 might prevent death in people with blood infections. Effects of coenzyme Q10 on myocardial protection during cardiac valve replacement and scavenging free radical activity in vitro. View abstract. Cochrane Database Syst.Rev. Studies on coenzyme Q10 and essential hypertension. View abstract. Distilled water in Amsterdam - Amsterdam Forum - Tripadvisor J Am Osteopath.Assoc. Coenzyme Q10 treatment in mitochondrial encephalomyopathies. Gazdikova, K., Gvozdjakova, A., Kucharska, J., Spustova, V., Braunova, Z., and Dzurik, R. [Effect of coenzyme Q10 in patients with kidney diseases]. Tan JT, Barry AR. View abstract. Acta Neurol Belg. Yaghini O, Hoseini N, Ghazavi MR, et al. View abstract. J Endocrinol Invest 2009;32(7):626-632. Current Therapeutic Research 1990;47(5):841-845. Orsucci, D., Filosto, M., Siciliano, G., and Mancuso, M. Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction. Brief content visible, double tap to read full content. 2010;88(3):e78-e86. View abstract. van Gaal L, Folkers K and Yamamura Y. Exploratory study of coenzyme Q10 in obesity. BMJ Open. Cochrane Database Syst.Rev. Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Mol.Aspects Med 1994;15 Suppl:s143-s147. Inhibition of coenzyme Q10 enzymes by clinically used anti-hypertensive drugs. Full content visible, double tap to read brief content. 2015 Jun;35(3):338-40. doi: 10.1097/JCP.0000000000000326. Coenzyme Q 10 improves lactic acidosis, strokelike episodes, and epilepsy in a patient with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes). Meier, T., Perlman, S. L., Rummey, C., Coppard, N. J., and Lynch, D. R. Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study. Expect More. View abstract. Folkers, K., Morita, M., and McRee, J., Jr. Fumagalli, S., Fattirolli, F., Guarducci, L., Cellai, T., Baldasseroni, S., Tarantini, F., Di, Bari M., Masotti, G., and Marchionni, N. Coenzyme Q10 terclatrate and creatine in chronic heart failure: a randomized, placebo-controlled, double-blind study. View abstract. Eur J Nutr. View abstract. 2010;41(1):110-113. A., Shu, X. O., Li, H., Ji, B., Cai, Q., Chai, W., and Zheng, W. Low plasma coenzyme Q(10) levels and breast cancer risk in Chinese women. What treatments can help with osteoporosis. CNS Neurosci Ther. Am J Cardiol. Heart Lung Circ 2010;19(10):584-591. The mitochondrial free radical theory of ageing--where do we stand? View abstract. 7-15-2010;25(9):1262-1268. Tawankanjanachot, I., Channarong, N. S., and Phanthumchinda, K. Auditory symptoms: a critical clue for diagnosis of MELAS. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Kuriyama N, Nakamura T, Nakazawa H, et al. Cooney, R. V., Dai, Q., Gao, Y. T., Chow, W. H., Franke, A. View abstract. View abstract. 1997;42(2):261-264. View abstract. Nutr Rev. J Investig Med. Coenzyme Q10 for heart failure. (Tokyo) 2010;56(1):77-81. View abstract. Donnino MW, Mortensen SJ, Andersen LW, Chase M, Berg KM, Balkema J, et al. Cochrane.Database.Syst.Rev. Pogessi L, Galanti G, Corneglio M, and et al. View abstract. A., Desnuelle, C., and Weiller, P. J. Damian, M. S., Ellenberg, D., Gildemeister, R., Lauermann, J., Simonis, G., Sauter, W., and Georgi, C. Coenzyme Q10 combined with mild hypothermia after cardiac arrest: a preliminary study. Mizuno, K., Tanaka, M., Nozaki, S., Mizuma, H., Ataka, S., Tahara, T., Sugino, T., Shirai, T., Kajimoto, Y., Kuratsune, H., Kajimoto, O., and Watanabe, Y. Antifatigue effects of coenzyme Q10 during physical fatigue. View abstract. Neurotherapeutics. View abstract. Biomedical and Clinical Aspects of Coenzyme Q10. A secondary analysis of a randomized clinical trial. Biochemical and clinical aspects of Coenzyme Q10. Rengo F, Abete P, Landino P, et al. Other studies show no benefit of taking coenzyme Q10 for lowering total cholesterol or LDL or increasing HDL (or "good" cholesterol) levels. Effects of coenzyme Q10 on health-related quality of life, clinical disease activity and blood pressure in patients with mild to moderate ulcerative colitis: a randomized clinical trial. Stocker, R., Bowry, V. W., and Frei, B. Ubiquinol-10 protects human low density lipoprotein more efficiently against lipid peroxidation than does alpha-tocopherol. A., Kwon, E. K., Koperski, S., and Evans, M. A. Amyotrophic lateral sclerosis-like conditions in possible association with cholesterol-lowering drugs: an analysis of patient reports to the University of California, San Diego (UCSD) Statin Effects Study. Molyneux, S. L., Florkowski, C. M., Richards, A. M., Lever, M., Young, J. M., and George, P. M. Coenzyme Q10; an adjunctive therapy for congestive heart failure? Biofactors 2008;32(1-4):221-230. Aure, K., Benoist, J. F., Ogier, de Baulny, Romero, N. B., Rigal, O., and Lombes, A. Med Sci Monit. J Clin Pharmacol 1990;30:596-608. View abstract. View abstract. Arterioscler Thromb Vasc Biol 1997;17:127-33. Muscle Nerve 2011;44(2):174-178. Sival, D. A., du Marchie Sarvaas, G. J., Brouwer, O. F., Uges, D. R., Verschuuren-Bemelmans, C. C., Maurits, N. M., Brunt, E. R., and van der Hoeven, J. H. Neurophysiological evaluation in children with Friedreich's ataxia. View abstract. View abstract. Caramia, G., Cocchi, M., Tonello, L., and Visci, G. 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Phase I study of lovastatin, an inhibitor of the mevalonate pathway, in patients with cancer. Palacka, P., Kucharska, J., Murin, J., Dostalova, K., Okkelova, A., Cizova, M., Waczulikova, I., Moricova, S., and Gvozdjakova, A. Complementary therapy in diabetic patients with chronic complications: a pilot study. Effects of Coenzyme Q10 Supplementation on Anthropometric Indices in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. : View abstract. Vitamin D3 1000 IU (250 Softgels) by Life Extension at the Vitamin Shoppe. [Investigation of the preventive effect of CoQ10 against the side- effects of anthracycline antineoplastic agents]. Molec Aspects Med 1994;15:S241-8. Some early research suggests that taking coenzyme Q10 improves kidney function in people with kidney failure. Yikoski T, Piirainen J, Hanninen O, and et al. A meta-analysis. Potential interactions between alternative therapies and warfarin. RN 2000;63:107. 2011;(6):CD003917. View abstract. 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Below are the general recommended daily amounts of vitamin D. The recommended daily amount for pregnant or nursing people is 600 IU/15 mcg. Arch Phys.Med Rehabil. Parashos, S. A., Swearingen, C. J., Biglan, K. M., Bodis-Wollner, I., Liang, G. S., Ross, G. W., Tilley, B. C., and Shulman, L. M. Determinants of the timing of symptomatic treatment in early Parkinson disease: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience. This article discusses bone density scans and other tests for osteoporosis. Zahler Junior D3 Chewable 1000iu, Great Tasting Chewable Vitamin D For : Clin Investig 1993;71:112-5. View abstract. View abstract. Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Strijks, E., Kremer, H. P., and Horstink, M. W. Q10 therapy in patients with idiopathic Parkinson's disease. 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Front Biosci 2008;13:6554-6579. Ho MJ, Li EC, Wright JM. View abstract. Bergamin, C. S., Rolim, L. C., Dib, S. A., and Moises, R. S. Unusual occurrence of intestinal pseudo obstruction in a patient with maternally inherited diabetes and deafness (MIDD) and favorable outcome with coenzyme Q10. Spurney, C. F., Rocha, C. T., Henricson, E., Florence, J., Mayhew, J., Gorni, K., Pasquali, L., Pestronk, A., Martin, G. R., Hu, F., Nie, L., Connolly, A. M., and Escolar, D. M. CINRG pilot trial of coenzyme Q10 in steroid-treated Duchenne muscular dystrophy. Karamali M, Gholizadeh M. The effects of coenzyme Q10 supplementation on metabolic profiles and parameters of mental health in women with polycystic ovary syndrome. Effects of coenzyme athletic performance system as an ergogenic aid on endurance performance to exhaustion. Plasma coenzyme Q (ubiquinone) concentrations in patients treated with simvastatin. View abstract. Mari D, Alleva R, Tomasetti M, and et al. Mol Aspects Med 1997;18:S159-68. No effect of combined coenzyme Q10 and selenium supplementation on atorvastatin-induced myopathy. View abstract. Textbook of Natural Medicine. XVI. View abstract. Drug Des Devel Ther. J Clin Lipidol. Ramirez-Tortosa, M. C., Quiles, J. L., Battino, M., Granados, S., Morillo, J. M., Bompadre, S., Newman, H. N., and Bullon, P. Periodontitis is associated with altered plasma fatty acids and cardiovascular risk markers. View abstract. At the end of the study, the prevalence of osteoporosis in the intervention group was significantly lower than in the control group. 2011;131(5):512-517. Ogasahara, S., Nishikawa, Y., Yorifuji, S., Soga, F., Nakamura, Y., Takahashi, M., Hashimoto, S., Kono, N., and Tarui, S. Treatment of Kearns-Sayre syndrome with coenzyme Q10. Nutrition 2012;28(7-8):767-772. View abstract. [RETRACTED]. View abstract. View abstract. View abstract. Langsjoen PH, Vadhanavikit S, Folkers K. Effective treatment with coenzyme Q10 of patients with chronic myocardial disease. Am J Cardiol 1990;65:521-3. View abstract. View abstract. Rivara MB, Yeung CK, Robinson-Cohen C, et al. Molyneux, S. L., Florkowski, C. M., George, P. M., Pilbrow, A. P., Frampton, C. M., Lever, M., and Richards, A. M. Coenzyme Q10: an independent predictor of mortality in chronic heart failure. Fetoni, A. R., Garzaro, M., Ralli, M., Landolfo, V., Sensini, M., Pecorari, G., Mordente, A., Paludetti, G., and Giordano, C. The monitoring role of otoacoustic emissions and oxidative stress markers in the protective effects of antioxidant administration in noise-exposed subjects: a pilot study. J Rehabil.Med 2008;40(9):773-775. 2014;84(5-6):252-60. 4-16-2001;174(8):421. Castro-Marrero J, Segundo MJ, Lacasa M, Martinez-Martinez A, Sentaes RS, Alegre-Martin J. On occasion, manufacturers may improve or change their product formulas and update their labels. Weyer G, Babej-Dolle RM, Hadler D, et al. The effect of coenzyme Q10 on idiopathic chronic dilated cardiomyopathy in children. Liu, Z. X. and Artmann, C. Relative bioavailability comparison of different coenzyme Q10 formulations with a novel delivery system. 2015 Dec;23(6):789-93. Taking coenzyme Q10 by mouth daily appears to lower systolic blood pressure (the top number) in some people with high systolic blood pressure but normal diastolic blood pressure (the bottom number). Participants in the control group did not receive this treatment. Bresolin, N., Bet, L., Binda, A., Moggio, M., Comi, G., Nador, F., Ferrante, C., Carenzi, A., and Scarlato, G. Clinical and biochemical correlations in mitochondrial myopathies treated with coenzyme Q10. View abstract. View abstract. View abstract. View abstract. Scand Cardiovasc J 2013;47(2):80-7. Study of periodontal disease and coenzyme Q. Res Commun Chem Pathol Pharmacol 1975;11:265-71. Combined treatment of coenzyme Q10 and aprotinin with intraaortic balloon pumping following aorto-coronary bypass surgery. View abstract. View abstract. 2021 Feb 3;(2)(2):CD008684.
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